Re: [R] Frailty model -- Conditional or Marginal?

From: Thomas Lumley <tlumley_at_uw.edu>
Date: Thu, 10 Mar 2011 12:55:21 +1300

On Thu, Mar 10, 2011 at 6:33 AM, hongsheng wu <comp611_at_gmail.com> wrote:
> Dear all,
>
> When I ran a frailty model like,
>
> model <- coxph(Surv(Day, Indicator) ~ trt + frailty(group,
> distribution="gaussian"))
>
> The variance of effect estimate of trt was estimated by conditional model or
> marginal model?

The frailty model is a conditional model, that is, the hazards for different treatment groups are assumed proportional conditional on the frailty.

     -thomas

-- 
Thomas Lumley
Professor of Biostatistics
University of Auckland

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Received on Wed 09 Mar 2011 - 23:58:42 GMT

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