Re: [R] Adjusting p values of a matrix

From: Bert Gunter <gunter.berton_at_gene.com>
Date: Mon, 04 Apr 2011 08:54:32 -0700

  1. This is not an R question, AFAICS.
  2. Sounds like a research topic. I don't think there's a meaningful simple answer. I suspect it strongly depends on the model and context.
    • Bert

On Mon, Apr 4, 2011 at 8:02 AM, January Weiner <january.weiner_at_mpiib-berlin.mpg.de> wrote:
> Dear all,
>
> I have an n x n matrix of p-values. The matrix is symmetrical, as it
> describes the "each against each" p values of correlation
> coefficients.
>
> How can I best correct the p values of the matrix? Notably, the total
> number of the tests performed is n(n-1)/2, since I do not test the
> correlation of each variable with itself. That means, I only want to
> correct one half of the matrix, not including the diagonal. Therefore,
> simply writing
>
> pmat <- p.adjust( pmat, method= "fdr" )
> # where pmat is an n x n matrix
>
> ...doesn't cut it.
>
> Of course, I can turn the matrix in to a three column data frame with
> n(n-1)/2 rows, but that is slow and not elegant.
>
> regards,
> j.
>
> --
> -------- Dr. January Weiner 3 --------------------------------------
> Max Planck Institute for Infection Biology
> Charitéplatz 1
> D-10117 Berlin, Germany
> Web   : www.mpiib-berlin.mpg.de
> Tel     : +49-30-28460514
>
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-- 
"Men by nature long to get on to the ultimate truths, and will often
be impatient with elementary studies or fight shy of them. If it were
possible to reach the ultimate truths without the elementary studies
usually prefixed to them, these would not be preparatory studies but
superfluous diversions."

-- Maimonides (1135-1204)

Bert Gunter
Genentech Nonclinical Biostatistics

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Received on Mon 04 Apr 2011 - 15:57:34 GMT

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