[R] Confidence interval for the difference between proportions - method used in prop.test()

From: Stefanie Von Felten <SVonfelten_at_uhbs.ch>
Date: Tue, 05 Apr 2011 12:38:34 +0200


Does anyone know which method from Newcombe (1998)* is implemented in prop.test for comparing two proportions? I would guess it is the method based on the Wilson score (for single proportion), with and without continuity correction for prop.test(..., correct=FALSE) and prop.test(..., correct=TRUE). These methods would correspond to no. 10 and 11 tested in Newcombe, respectively. Can someone confirm this? If not, which other methods are implemented by prop.test?

There is also the function ci.pd() from the R-package Epi, which should implement method no. 10 from Newcombe. However, prop.test(..., correct=FALSE) and ci.pd do not give the same result if I do the following:

successes <- c(21, 41)
total <- c(345, 345)
prop.test(successes, total, correct=FALSE) library(Epi)
ci.pd(matrix(c(successes, total-successes),ncol=2, byrow=TRUE))

Can someone explain why?

Best wishes
Stefanie von Felten

Stefanie von Felten, PhD
Clinical Trial Unit, CTU
University Hospital Basel
Schanzenstrasse 55
CH-4031 Basel

Phone: ++41(0)61 556 54 98

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