[R] Correlation to a Single Gene

From: Damion Colin Nero <dcn208_at_nyu.edu>
Date: Wed 17 Jan 2007 - 16:12:57 GMT

I am trying to find a way to perform pairwise correlations against one gene in a matrix rather than computing every pairwise correlation. I am interested in how 1 transcription factor correlates to every gene in a matrix of 55 experiments (columns) by 23,000 genes (rows), performing the correlation by rows. Trying to perform every pairwise correlation in this fashion is too memory intensive for any computer I am currently using so I am wondering if anyone had a method for doing pairwise correlations to a single gene or if there is a preexisting package in R that might address this.

Damion Nero
Plant Molecular Biology Lab
Department of Biology
New York University

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