Re: [R] convergence of coxfilter and coxph

From: Thomas Lumley <tlumley_at_u.washington.edu>
Date: Tue, 22 May 2007 09:05:49 -0700 (PDT)

On Mon, 21 May 2007, carol white wrote:

> Hi, coxfilter function in genefilter package uses coxph to fit a model
> to filter genes. how come that coxfilter could converge to find a
> solution in cox model fitting using a data matrix of 8000 variables and
> 600 samples but coxph doesn't converge with the same matrix?

coxfilter() fits 8000 one-variable models, which works (for appropriate values of "works"). coxph() refuses to fit one 8000-variable model.

         -thomas



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