[R] weighted inverse chi-square method for combining p-values

From: Andreas Cederfeldt <andreas.cederfeldt_at_gmail.com>
Date: Wed, 25 Jun 2008 12:32:50 +0200


This is more of a general question than a pure R one, but I hope that is OK. I want to combine one-tailed independent p-values using the weighted version of fisher's inverse chi-square method. The unweighted version is pretty straightforward to implement. If x is a vector with p-values, then I guess that this will do for the unweighted version:

statistic <- -2*sum(log(x))
comb.p <- 1-pchisq(statistic,2*length(x))

Has anyone written some R code for the weighted version?

Anders Cederfeldt

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