[R] one-site competition data // curve fitting

From: Thiemo Schreiber <schreibe_at_biochem.mpg.de>
Date: Mon, 07 Jul 2008 11:15:57 +0200


Hello everyone,

I have biological data from a competition experiment where a free ligand is titrated against the binding of a protein.

Now, I would like to fit a standard on-site binding curve to this data in order to obtain the IC50 and Kd values. Unfortunately I have not been able to find a package/function which allows such a fitting and calculates the results.

Does anyone know if there is a suitable package available and which function to apply?

Thanks a lot.

Cheers
Thiemo Schreiber

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