Re: [R] linear models and colinear variables...

From: Jonathan Baron <>
Date: Fri 02 Jul 2004 - 12:43:36 EST

On 07/01/04 17:53, Peter Gaffney wrote:
>> When you do this, you are including all the
>> interaction terms.
>> The * indicates an interaction, as opposed to +.
>In this particular case I need to do exactly this;
>this is a study of antibiotic resistance - two of the
>variables respectively are type of bacteria and
>antibacterial agent. The evolutionary/epidemiological

Then you should use at most the interaction of every agent with every germ. Including all the interaction terms means that you look at germ*germ and drug*drug interactions too.

>behavior of each pairing of these factors is
>different. Can I remove some lower order terms; for
>example, if I get rid of Bugtype:Usage.level.ofdrug
>and Drugtype:Usage.level.of.drug will
>Bugtype:Drugtype:Usage.level.of.drug still be valid?

I don't think this example is "removing lower order terms," or else I don't understand it. I think it is what I was just saying. You would want something like (to use my terms), germ1*drug1 + germ1*drug2 + ... + germN*drug(M-1) + germN*drugM. Each of these would automatically include the relevant first-order terms. For example, germ1*drug1 would include germ1 and drug1 effects alone. And I think you want those, if you are really interested in the interaction. Otherwise, what you think is an interaction could just be a main effect.

But I really don't understand this setup. It sounds like each observation consists of a randomly chosen SET of germs and a SET of drugs, so you can classify each data point in terms of the presence or absence of each germ and the presence or absence of each drug. Is that it? It isn't crazy, but it is unusual.


Jonathan Baron, Professor of Psychology, University of Pennsylvania
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Received on Fri Jul 02 12:48:18 2004

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