[R] FWER + multiple linear models

From: Serguei Baranov <barano_s_at_molgen.mpg.de>
Date: Sat 31 Jul 2004 - 01:33:15 EST


Could someone kindly help me with the following question: when I analyze microarray data I need to fit multiple linear regression models between genes and clinical patameters followed by estimation of the p-values.
What's the solution to implement Westfall and Young's algorithm + resampling into the scheme:
lm -> stepAIC -> anova.
Actually permcor works fine for me in the case of one regression variable, I need extension for multiple regression models. Any ideas are very much wellcome!

Sincerely yours,
Serguei Baranov
Research "Obesity & Hypertension"
MPI of Molecular Genetics, Ihnestr. 73, 14195, Berlin, Germany phone: +49 30 84131238
fax: +49 30 84131228



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