[R] Re: Repeated Measures, groupedData and lme

From: Keith Wong <keithw_at_med.usyd.edu.au>
Date: Sat 19 Mar 2005 - 10:40:47 EST

Hello,

I'm an R-newbie, but I've been learning to use lme for repeated measures experiments as well.

If I understand correctly:
  Outcome variable: Mg (Kg/ha)
  Subject/grouping variable: block

  Condition/treatment: treatment (19 levels)   Repeated factor: time (3 levels: 99, 02, 04)

I think if you specify the model formula in the lme call, then the formula structure specified in the groupedData object is ignored.

One suggestion for the model:

Model1<-lme(mg~treatment + year + treatment:year, random=~1|block, data=magnesium)

If the question of interest is the treatment:year interaction

Or
Model2 <- lme(mg~treatment, random=~1|block, data=magnesium)

Hope this helps ... and hope the experts chime in at this point to give more guidance.

Keith

------quoting original post---
Hello

I am trying to fit a REML to some soil mineral data which has been collected over the time period 1999 - 2004. I want to know if the 19 different treatments imposed, differ in terms of their soil mineral content. A tree model of the data has shown differences between the treatments can be attributed to the Magnesium, Potassium and organic matter content of the soil, with Magnesium being the primary separating variable.

I am looking at soil mineral data were collected : 99, 02, 04.

In the experiment, there are 19 different treatments (treatmentcontrol, treatment6TFYM, treatment 12TFYM etc), which are replicated in 3 blocks.

For the magnesium soil data, I have created the following groupedData object:

magnesium<-groupedData(Mg~year|treatment, inner=~block) Where mg=magnesium Kg/ha

As it is a repeated measures I was going to use an lme. I have looked at Pinherio and Bates : Mixed-Effects models in S and S-plus and I am getting slightly confused. In order to fit the lme, should I specify the data to use in the model as the grouped structure model?

If so is the following command correct:

Model1<-lme(mg~treatment, random=block|year, data=magnesium)?

I am slightly worried that it isn't, because in model summary, instead of listing the 19 different treatments in the fixed effects section, it writes intercept (as normal), then treatment^1, treatment^2 etc.

However if I don't specify the groupedData object in the model, then in the fixed effects section, it names the treatments (i.e. intercept, treatmentcontrol, treatment6TFYM.

Should I be fitting the model using the whole data set rather than the groupedData object?

Thank you very much for your help

Emma Pilgrim



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