[R] global normalization

From: NATALIA F TCHETCHERINA <nxt7_at_psu.edu>
Date: Thu 26 May 2005 - 08:33:05 EST


Hello all,
I have question about global normalization. I have data from big experement(two-color cDNA arrays) where used three different layouts but the same set of genes. I used limma package for within array normalization. My question is: how I can do between array normalization (global) if arrays have different layout(different location and different number technical replicates (number of spots of a gene on an array))?

Sincerely, Natalia.



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