Re: [R] Binary outcome with non-absorbing outcome state

From: Frank Funderburk <frankfunder_at_earthlink.net>
Date: Fri 29 Jul 2005 - 23:43:42 EST


Singer & Willett (2003) also cover this ground.

Singer, JD & Willett, JB (2003). Applied longitudinal data analysis: Modeling change and event occurrence. New Yok: Oxford University Press.

-----Original Message-----
From: Frank E Harrell Jr <f.harrell@vanderbilt.edu> Sent: Jul 29, 2005 9:25 AM
To: John Sorkin <jsorkin@grecc.umaryland.edu> Cc: R-help@stat.math.ethz.ch
Subject: Re: [R] Binary outcome with non-absorbing outcome state

John Sorkin wrote:
> I am trying to model data in which subjects are followed through time to
> determine if they fall, or do not fall. Some of the subjects fall once,
> some fall several times. Follow-up time varies from subject to subject.
> I know how to model time to the first fall (e.g. Cox Proportional
> Hazards, Kaplan-Meir analyses, etc.) but I am not sure how I can model
> the data if I include the data for those subjects who fall more than
> once. I would appreciate suggestions about a models that I could use,
> how I would quantify the follow-up time, how I account for the imbalance
> in the data (some subjects would contribute one outcome measure, others
> multiple measures), etc.
>
> Many thanks,
> John

A great reference for this is

@Book{the00mod,

   author =               {Therneau, Terry and Grambsch, Patricia},
   title =                {Modeling Survival Data: Extending the Cox Model},
   publisher =    {Springer-Verlag},
   year =                 2000,
   address =              {New York}

}

Frank

>
> John Sorkin M.D., Ph.D.
> Chief, Biostatistics and Informatics
> Baltimore VA Medical Center GRECC and
> University of Maryland School of Medicine Claude Pepper OAIC
>
> University of Maryland School of Medicine
> Division of Gerontology
> Baltimore VA Medical Center
> 10 North Greene Street
> GRECC (BT/18/GR)
> Baltimore, MD 21201-1524
>
> 410-605-7119
> --- NOTE NEW EMAIL ADDRESS:
> jsorkin@grecc.umaryland.edu
>
> [[alternative HTML version deleted]]
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-- 
Frank E Harrell Jr   Professor and Chair           School of Medicine
                      Department of Biostatistics   Vanderbilt University

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Frank Funderburk
 
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Received on Fri Jul 29 23:53:56 2005

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