From: <ptr2003_at_columbia.edu>

Date: Tue 18 Oct 2005 - 04:09:27 EST

R-help@stat.math.ethz.ch mailing list

https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide! http://www.R-project.org/posting-guide.html Received on Tue Oct 18 04:17:46 2005

Date: Tue 18 Oct 2005 - 04:09:27 EST

Dear R users,

I have been using the pdMat class "pdIdnot" (from the mgcv package)instead of "pdIdent" to avoid overflow in GLMM fits with the MASS package function glmmPQL, of the following form:

fit1 <- glmmPQL(fixed=y0~-1+xx0, random=list(gp=pdIdent(~-1+zz0)),

family=binomial) # vulnerable to overflow fit2 <- glmmPQL(fixed=y0~-1+xx0, random=list(gp=pdIdnot(~-1+zz0)), family=binomial) # overflow-proof

In instances in which fit1 does *not* lead to overflow, the result sometimes differs from fit2. This leads me to two questions.

- Does anyone have any thoughts on what might cause such a discrepancy?
- Given two discrepant fits, I would like a way to choose the better one. If my reading of Breslow and Clayton's 1993 paper (specifically, their equation 12) is correct, at convergence, the profile quasilikelihood should be approximately equal to the log likelihood from the last linear mixed model fit by the algorithm. If so, the $logLik component of the lme object produced by glmmPQL should approximate the quasilikelihood I am trying to maximize. In short: according to this argument, the glmmPQL fit with higher "logLik" should be the better one.

And yet, some previous postings seem to indicate that the "logLik" of an object produced by glmmPQL cannot be interpreted in terms of likelihood, quasi or otherwise. If the above made sense (or even if not), is there anyone who could kindly speak to this point?

Any help with either of the above questions would be greatly appreciated.

Phil Reiss

PhD candidate, Dept. of Biostatistics

Columbia University, New York

ptr2003@columbia.edu

R-help@stat.math.ethz.ch mailing list

https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide! http://www.R-project.org/posting-guide.html Received on Tue Oct 18 04:17:46 2005

*
This archive was generated by hypermail 2.1.8
: Sun 23 Oct 2005 - 19:00:36 EST
*