Re: [R] least square fit with non-negativity constraints for absorption spectra fitting

From: Lu Yuefeng <>
Date: Sat 15 Jul 2006 - 00:34:07 EST

Were you doing blind deconvolution or the spectrum basis are assummed to be known?

As for blind deconvolution, alternatively you might consider alternating least square, non-negative matrix factorization, or independent component analysis + alternating least square as the post-processing.


On 7/11/06, Xu, Xiuli (NIH/NHLBI) [E] <> wrote:
> I would really appreciate it if someone can give suggestions on how to
> do spectra fitting in R using ordinary least square fitting and
> non-negativity constraints. The lm() function works well for ordinary
> least square fitting, but how to specify non-negativity constraints? It
> wouldn't make sense if the fitting coefficients coming out as negative
> in absorption spectra deconvolution.
> Thanks.
> Xiuli
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        [[alternative HTML version deleted]] mailing list PLEASE do read the posting guide! Received on Sat Jul 15 00:39:46 2006

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